KCNA1 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-66980-60UL
120 ul
£317.00
E-AB-66980-120UL
200 ul
£492.00
E-AB-66980-200UL
About this Product
- SKU:
- E-AB-66980
- Additional Names:
- AEMK,EA1,HBK1,HUK1,KCNA1,KV1.1,MBK1,MK1,RBK1
- Application:
- Immunofluorescence
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human KCNA1 (NP_000208.2).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-kcna1_polyclonal_antibody-e_ab_66980
