THRB Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-66591-60UL
120 ul
£317.00
E-AB-66591-120UL
200 ul
£492.00
E-AB-66591-200UL
About this Product
- SKU:
- E-AB-66591
- Additional Names:
- C-ERBA-2,C-ERBA-BETA,ERBA2,GRTH,NR1A2,PRTH,THR1,THRB,THRB1,THRB2
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human THRB
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-thrb_polyclonal_antibody-e_ab_66591
