RTN3 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-66432-60UL
120 ul
£317.00
E-AB-66432-120UL
200 ul
£492.00
E-AB-66432-200UL
About this Product
- SKU:
- E-AB-66432
- Additional Names:
- ASYIP,HAP,NSPL2,NSPLII,RTN3,RTN3-A1
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human RTN3 (NP_006045.1).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-rtn3_polyclonal_antibody-e_ab_66432
