LRP6 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-66414-60UL
120 ul
£317.00
E-AB-66414-120UL
200 ul
£492.00
E-AB-66414-200UL
About this Product
- SKU:
- E-AB-66414
- Additional Names:
- ADCAD2,LRP6,STHAG7
- Application:
- Immunofluorescence
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human LRP6 (NP_002327.2).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-lrp6_polyclonal_antibody-e_ab_66414
