NOTCH3 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-66095-60UL
120 ul
£317.00
E-AB-66095-120UL
200 ul
£492.00
E-AB-66095-200UL
About this Product
- SKU:
- E-AB-66095
- Additional Names:
- CADASIL,CADASIL1,CASIL,IMF2,LMNS,NOTCH3,notch 3
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human NOTCH3 (NP_000426.2).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-notch3_polyclonal_antibody-e_ab_66095
