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Antibodies

RAD51C Polyclonal Antibody

Product Sizes
60 ul
£217.00
E-AB-65915-60UL
120 ul
£317.00
E-AB-65915-120UL
200 ul
£492.00
E-AB-65915-200UL
About this Product
SKU:
E-AB-65915
Additional Names:
BROVCA3,FANCO,R51H3,RAD51C,RAD51L2
Application:
Immunofluorescence
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human RAD51C (NP_002867.1).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody