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Antibodies

PGC1 alpha Polyclonal Antibody

Product Sizes
60 ul
£235.00
E-AB-65852-60UL
120 ul
£346.00
E-AB-65852-120UL
200 ul
£541.00
E-AB-65852-200UL
About this Product
SKU:
E-AB-65852
Additional Names:
LEM6,PGC-1(alpha),PGC-1alpha,PGC-1v,PGC1,PGC1 alpha,PGC1A,PPARG coactivator 1 alpha,PPARGC1,PPARGC1A
Application:
ELISA, IHC-Paraffin, Immunocytochemistry, Immunofluorescence, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Host:
Rabbit
Immunogen:
A synthetic peptide of human PGC1 alpha (NP_037393.1).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody