LGMN Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-65780-60UL
120 ul
£317.00
E-AB-65780-120UL
200 ul
£492.00
E-AB-65780-200UL
About this Product
- SKU:
- E-AB-65780
- Additional Names:
- AEP,LGMN,LGMN1,PRSC1,legumain
- Application:
- Immunofluorescence
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human LGMN (NP_001008530.1).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-lgmn_polyclonal_antibody-e_ab_65780
