Perforin Polyclonal Antibody
Product Sizes
60 ul
£235.00
E-AB-65660-60UL
120 ul
£346.00
E-AB-65660-120UL
200 ul
£541.00
E-AB-65660-200UL
About this Product
- SKU:
- E-AB-65660
- Additional Names:
- FLH2,HPLH2,P1,PFN1,PFP,PRF1,Perforin,perforin-1
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human Perforin (NP_001076585.1).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-perforin_polyclonal_antibody-e_ab_65660
