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Antibodies

CYTH1 Polyclonal Antibody

Product Sizes
60 ul
£217.00
E-AB-65277-60UL
120 ul
£317.00
E-AB-65277-120UL
200 ul
£492.00
E-AB-65277-200UL
About this Product
SKU:
E-AB-65277
Additional Names:
B2-1,CYTH1,CYTOHESIN-1,D17S811E,PSCD1,SEC7
Application:
Immunofluorescence
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human CYTH1 (NP_004753.1).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody