PTP4A2 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-65270-60UL
120 ul
£317.00
E-AB-65270-120UL
200 ul
£492.00
E-AB-65270-200UL
About this Product
- SKU:
- E-AB-65270
- Additional Names:
- HH13,HH7-2,HU-PP-1,OV-1,PRL-2,PRL2,PTP4A,PTP4A2,PTPCAAX2,ptp-IV1a,ptp-IV1b
- Application:
- Immunofluorescence, Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human PTP4A2 (NP_536316.1).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-ptp4a2_polyclonal_antibody-e_ab_65270
