RNASEH2A Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-65212-60UL
120 ul
£317.00
E-AB-65212-120UL
200 ul
£492.00
E-AB-65212-200UL
About this Product
- SKU:
- E-AB-65212
- Additional Names:
- AGS4,JUNB,RNASEH2A,RNASEHI,RNHIA,RNHL
- Application:
- Immunofluorescence, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human RNASEH2A (NP_006388.2).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-rnaseh2a_polyclonal_antibody-e_ab_65212
