XIAP Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-64526-60UL
120 ul
£317.00
E-AB-64526-120UL
200 ul
£492.00
E-AB-64526-200UL
About this Product
- SKU:
- E-AB-64526
- Additional Names:
- API3,BIRC4,IAP-3,ILP1,MIHA,XIAP,XLP2,hIAP-3,hIAP3
- Application:
- Immunofluorescence
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human XIAP (NP_001158.2).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-xiap_polyclonal_antibody-e_ab_64526
