UNC13D Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-64476-60UL
120 ul
£317.00
E-AB-64476-120UL
200 ul
£492.00
E-AB-64476-200UL
About this Product
- SKU:
- E-AB-64476
- Additional Names:
- FHL3,HLH3,HPLH3,Munc13-4,UNC13D
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human UNC13D (NP_954712.1).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-unc13d_polyclonal_antibody-e_ab_64476
