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Antibodies

HDAC3 Polyclonal Antibody

Product Sizes
60 ul
£235.00
E-AB-64237-60UL
120 ul
£346.00
E-AB-64237-120UL
200 ul
£541.00
E-AB-64237-200UL
About this Product
SKU:
E-AB-64237
Additional Names:
HD3,HDAC3,RPD3,RPD3-2
Application:
Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Host:
Rabbit
Immunogen:
A synthetic peptide of human HDAC3 (NP_003874.2).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody