CEBPA Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-64040-60UL
120 ul
£317.00
E-AB-64040-120UL
200 ul
£492.00
E-AB-64040-200UL
About this Product
- SKU:
- E-AB-64040
- Additional Names:
- C/EBP-alpha,CEBP,CEBPA
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human CEBPA (NP_004355.2).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cebpa_polyclonal_antibody-e_ab_64040
