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Antibodies

HDAC4 Polyclonal Antibody

Product Sizes
60 ul
£217.00
E-AB-63997-60UL
120 ul
£317.00
E-AB-63997-120UL
200 ul
£492.00
E-AB-63997-200UL
About this Product
SKU:
E-AB-63997
Additional Names:
AHO3,BDMR,HA6116,HD4,HDAC-4,HDAC-A,HDAC4,HDACA
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human HDAC4 (NP_006028.2).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody