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Antibodies

CHD3 Polyclonal Antibody

Product Sizes
60 ul
£217.00
E-AB-63718-60UL
120 ul
£317.00
E-AB-63718-120UL
200 ul
£492.00
E-AB-63718-200UL
About this Product
SKU:
E-AB-63718
Additional Names:
CHD3,Mi-2a,Mi2-ALPHA,ZFH
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Host:
Rabbit
Immunogen:
A synthetic peptide of human CHD3 (NP_001005273.1).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody