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Antibodies

SOCS3 Polyclonal Antibody

Product Sizes
60 ul
£235.00
E-AB-63265-60UL
120 ul
£346.00
E-AB-63265-120UL
200 ul
£541.00
E-AB-63265-200UL
About this Product
SKU:
E-AB-63265
Additional Names:
ATOD4,CIS3,Cish3,SOCS-3,SOCS3,SSI-3,SSI3
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
Host:
Rabbit
Immunogen:
A synthetic peptide of human SOCS3 (NP_003946.3).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody