CAD Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-62648-60UL
120 ul
£317.00
E-AB-62648-120UL
200 ul
£492.00
E-AB-62648-200UL
About this Product
- SKU:
- E-AB-62648
- Additional Names:
- CAD,CDG1Z,EIEE50,GATD4
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human CAD (NP_004332.2).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cad_polyclonal_antibody-e_ab_62648
