NUDT15 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-62476-60UL
120 ul
£317.00
E-AB-62476-120UL
200 ul
£492.00
E-AB-62476-200UL
About this Product
- SKU:
- E-AB-62476
- Additional Names:
- MTH2,NUDT15,NUDT15D
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human NUDT15 (NP_060753.1).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-nudt15_polyclonal_antibody-e_ab_62476
