(KO Validated) HIRA Polyclonal Antibody
Product Sizes
60 ul
£234.00
E-AB-62250-60UL
120 ul
£350.00
E-AB-62250-120UL
200 ul
£533.00
E-AB-62250-200UL
About this Product
- SKU:
- E-AB-62250
- Additional Names:
- DGCR1,HIRA,TUP1,TUPLE1
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human HIRA (NP_003316.3).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-(ko_validated)_hira_polyclonal_antibody-e_ab_62250
