CDKN2C Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-61784-60UL
120 ul
£317.00
E-AB-61784-120UL
200 ul
£492.00
E-AB-61784-200UL
About this Product
- SKU:
- E-AB-61784
- Additional Names:
- CDKN2C,INK4C,p18,p18-INK4C
- Application:
- Immunofluorescence, Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human CDKN2C (NP_523240.1).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-cdkn2c_polyclonal_antibody-e_ab_61784
