LDB3 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-61722-60UL
120 ul
£317.00
E-AB-61722-120UL
200 ul
£492.00
E-AB-61722-200UL
About this Product
- SKU:
- E-AB-61722
- Additional Names:
- CMD1C,CMH24,CMPD3,CYPHER,LDB3,LDB3Z1,LDB3Z4,LVNC3,MFM4,ORACLE,PDLIM6,ZASP
- Application:
- Immunofluorescence
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified, all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human LDB3 (NP_001073585.1).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-ldb3_polyclonal_antibody-e_ab_61722
