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Antibodies

RNF7 Polyclonal Antibody

Product Sizes
60 ul
£217.00
E-AB-61633-60UL
120 ul
£317.00
E-AB-61633-120UL
200 ul
£492.00
E-AB-61633-200UL
About this Product
SKU:
E-AB-61633
Additional Names:
CKBBP1,RNF7,ROC2,SAG
Application:
Immunofluorescence
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human RNF7 (NP_055060.1).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody