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Antibodies

HDAC5 Polyclonal Antibody

Product Sizes
60 ul
£217.00
E-AB-61573-60UL
120 ul
£317.00
E-AB-61573-120UL
200 ul
£492.00
E-AB-61573-200UL
About this Product
SKU:
E-AB-61573
Additional Names:
HD5,HDAC5,NY-CO-9
Application:
Immunofluorescence
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
A synthetic peptide of human HDAC5 (NP_005465.2).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody