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Antibodies

PARN Polyclonal Antibody

Product Sizes
60 ul
£217.00
E-AB-61418-60UL
120 ul
£317.00
E-AB-61418-120UL
200 ul
£492.00
E-AB-61418-200UL
About this Product
SKU:
E-AB-61418
Additional Names:
DAN,DKCB6,PARN,PFBMFT4
Application:
Immunofluorescence, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human PARN (NP_002573.1).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody