DNMT3B Polyclonal Antibody
Product Sizes
60 ul
£235.00
E-AB-60798-60UL
120 ul
£346.00
E-AB-60798-120UL
200 ul
£541.00
E-AB-60798-200UL
About this Product
- SKU:
- E-AB-60798
- Additional Names:
- DNMT3B,ICF,ICF1,M.HsaIIIB
- Application:
- Immunofluorescence, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human DNMT3B
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-dnmt3b_polyclonal_antibody-e_ab_60798
