PTPN11 Polyclonal Antibody
Product Sizes
60 ul
£217.00
E-AB-60785-60UL
120 ul
£317.00
E-AB-60785-120UL
200 ul
£492.00
E-AB-60785-200UL
About this Product
- SKU:
- E-AB-60785
- Additional Names:
- BPTP3,CFC,JMML,METCDS,NS1,PTP-1D,PTP2C,PTPN11,SH-PTP2,SH-PTP3,SHP2
- Application:
- Immunofluorescence, Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein of human PTPN11 (NP_002825.3).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-ptpn11_polyclonal_antibody-e_ab_60785
