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Antibodies

KCNQ1 Polyclonal Antibody

Product Sizes
60 ul
£217.00
E-AB-60659-60UL
120 ul
£317.00
E-AB-60659-120UL
200 ul
£492.00
E-AB-60659-200UL
About this Product
SKU:
E-AB-60659
Additional Names:
ATFB1,ATFB3,JLNS1,KCNA8,KCNA9,KCNQ1,KVLQT1,Kv1.9,Kv7.1,LQT,LQT1,RWS,SQT2,WRS
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human KCNQ1 (NP_861463.1).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody