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Antibodies

ACVR2A Polyclonal Antibody

Product Sizes
60 ul
£217.00
E-AB-60537-60UL
120 ul
£317.00
E-AB-60537-120UL
200 ul
£492.00
E-AB-60537-200UL
About this Product
SKU:
E-AB-60537
Additional Names:
ACTRII,ACVR2,ACVR2A
Application:
Immunofluorescence, Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human ACVR2A (NP_001607.1).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody