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Antibodies

AIRE Polyclonal Antibody

Product Sizes
60 ul
£217.00
E-AB-60437-60UL
120 ul
£317.00
E-AB-60437-120UL
200 ul
£492.00
E-AB-60437-200UL
About this Product
SKU:
E-AB-60437
Additional Names:
AIRE,AIRE1,APECED,APS1,APSI,PGA1
Application:
Immunofluorescence
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
Host:
Rabbit
Immunogen:
A synthetic peptide of human AIRE (NP_000374.1).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody