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Antibodies

CBS Polyclonal Antibody

Product Sizes
60 ul
£217.00
E-AB-60308-60UL
120 ul
£317.00
E-AB-60308-120UL
200 ul
£492.00
E-AB-60308-200UL
About this Product
SKU:
E-AB-60308
Additional Names:
CBS,HIP4
Application:
Immunofluorescence
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human CBS (NP_000062.1).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody