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Antibodies

Estrogen Receptor alpha Polyclonal Antibody

Product Sizes
60 ul
£235.00
E-AB-60073-60UL
120 ul
£346.00
E-AB-60073-120UL
200 ul
£541.00
E-AB-60073-200UL
About this Product
SKU:
E-AB-60073
Additional Names:
ER;ER alpha;ESR;ESR1;ESRA;ESTRR;Era;NR3A1
Application:
Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.
Host:
Rabbit
Immunogen:
Recombinant fusion protein of human Estrogen Receptor alpha (NP_000116.2).
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody