NF1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-53528-20UL
60 ul
£183.00
E-AB-53528-60UL
120 ul
£272.00
E-AB-53528-120UL
200 ul
£420.00
E-AB-53528-200UL
About this Product
- SKU:
- E-AB-53528
- Additional Names:
- DKFZp686J1293,FLJ21220,NF,Neurofibromatosis Noonan syndrome,Neurofibromatosis related protein NF 1,Neurofibromatosis related protein NF1,Neurofibromatosis-related protein NF-1,Neurofibromin 1,Neurofibromin truncated,Neurofibromin1,neurofibromatosis type I
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.7 mg/ml
- Extra Details:
- This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.NF1 (Neurofibromin 1) is a Protein Coding gene. Diseases associated with NF1 include Neurofibromatosis-Noonan Syndrome and Neurofibromatosis, Type 1. Among its related pathways are Development VEGF signaling via VEGFR2 - generic cascades and RET signaling. GO annotations related to this gene include binding and phosphatidylcholine binding.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human NF1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-nf1_polyclonal_antibody-e_ab_53528
