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Antibodies

EFNB1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-53525-20UL
60 ul
£183.00
E-AB-53525-60UL
120 ul
£272.00
E-AB-53525-120UL
200 ul
£420.00
E-AB-53525-200UL
About this Product
SKU:
E-AB-53525
Additional Names:
CFND,CFNS,Craniofrontonasal syndrome (craniofrontonasal dysplasia),EFL 3,EFL-3,EFL3,EFNB1,ELK ligand,ELK-L,EPH-related receptor tyrosine kinase ligand 2,EPLG2,Elk L,Eph related receptor tyrosine kinase ligand 2,Ephrin-B1,LERK 2,LERK-2,LERK2,Ligand o
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.9 mg/ml
Extra Details:
Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.
Host:
Rabbit
Immunogen:
Synthetic peptide of human EFNB1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody