PLA2G16 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-53452-20UL
60 ul
£183.00
E-AB-53452-60UL
120 ul
£272.00
E-AB-53452-120UL
200 ul
£420.00
E-AB-53452-200UL
About this Product
- SKU:
- E-AB-53452
- Additional Names:
- AdPLA;Adipose specific PLA2;Adipose specific phospholipase A2;Adipose-specific phospholipase A2;Ca independent phospholipase A1/2;Group XVI phospholipase A1/A2;Group XVI phospholipase A2;H REV107 1;H rev 107 protein homolog;H-rev 107 protein homolog;HRAS
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1.1 mg/ml
- Extra Details:
- Secretory phopholipase A2 (PLA2) enzymes cleave an acyl ester bond in the sn-2 position of glycerophospholipids. These extracellular proteins have a high disulfide bond content, low molecular mass (14 kDa), and require mM levels of Ca2+ for catalysis. They play a crucial role in the generation of arachidonates and eicosanoids, and have a number of biological actions including immunological responses, inflammation, cellular proliferation, vasoconstriction, and bronchioconstriction. Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity). N- and O-acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human PLA2G16
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-pla2g16_polyclonal_antibody-e_ab_53452
