MAFA Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-53394-20UL
60 ul
£183.00
E-AB-53394-60UL
120 ul
£272.00
E-AB-53394-120UL
200 ul
£420.00
E-AB-53394-200UL
About this Product
- SKU:
- E-AB-53394
- Additional Names:
- HMafA,MAFA,Mafa,Pancreatic beta cell specific transcriptional activator,Pancreatic beta-cell-specific transcriptional activator,RIPE3b1,Transcription factor MafA,Transcription factor RIPE3b1,v maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.2 mg/ml
- Extra Details:
- Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human MAFA
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-mafa_polyclonal_antibody-e_ab_53394
