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Antibodies

XPC Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-53352-20UL
60 ul
£183.00
E-AB-53352-60UL
120 ul
£272.00
E-AB-53352-120UL
200 ul
£420.00
E-AB-53352-200UL
About this Product
SKU:
E-AB-53352
Additional Names:
DNA repair protein complementing XP C cells,DNA repair protein complementing XP-C cells,DNA repair protein complementing XPC cells ,RAD4,Xeroderma pigme,Xeroderma pigmentosum complementation group C,Xeroderma pigmentosum group C complementing protein,p125
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.66 mg/ml
Extra Details:
The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
Host:
Rabbit
Immunogen:
Synthetic peptide of human XPC
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody