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Antibodies

F3 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-53340-20UL
60 ul
£183.00
E-AB-53340-60UL
120 ul
£272.00
E-AB-53340-120UL
200 ul
£420.00
E-AB-53340-200UL
About this Product
SKU:
E-AB-53340
Additional Names:
CD142;CD142 antigen;Coagulation factor III;Coagulation factor III (thromboplastin tissue factor);F3;FLJ17960;TF;TFA;Thromboplastin;Tissue factor
Application:
Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
1.3 mg/ml
Extra Details:
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Synthetic peptide of human F3
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody