ATR Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-53308-20UL
60 ul
£183.00
E-AB-53308-60UL
120 ul
£272.00
E-AB-53308-120UL
200 ul
£420.00
E-AB-53308-200UL
About this Product
- SKU:
- E-AB-53308
- Additional Names:
- ATR,Ataxia telangiectasia and Rad3 related,Ataxia telangiectasia and Rad3-related protein,FCTCS,FRAP Related Protein 1,FRAP-related protein 1,FRP1,MEC1,MEC1 mitosis entry checkpoint 1 homolog,Protein kinase ATR,RAC3,Rad3 related protein,SCKL,SCKL1,Ser
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human ATR
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-atr_polyclonal_antibody-e_ab_53308
