HRAS Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-53241-20UL
60 ul
£183.00
E-AB-53241-60UL
120 ul
£272.00
E-AB-53241-120UL
200 ul
£420.00
E-AB-53241-200UL
About this Product
- SKU:
- E-AB-53241
- Additional Names:
- C BAS/HAS,C HA RAS1,CTLO,GTP and GDP binding peptide B,GTPase HRas,H RASIDX,H Ras 1,H-Ras-1,HAMSV,Ha Ras,Ha Ras1 proto oncoprotein,Ha-Ras,Harvey rat sarcoma viral o,N-terminally processed,c H ras,c has/bas p21 protein,c ras Ki 2 activated oncogene,c-H-ras
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.66 mg/ml
- Extra Details:
- This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human HRAS
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-hras_polyclonal_antibody-e_ab_53241
