ZBTB10 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-53220-20UL
60 ul
£183.00
E-AB-53220-60UL
120 ul
£272.00
E-AB-53220-120UL
200 ul
£420.00
E-AB-53220-200UL
About this Product
- SKU:
- E-AB-53220
- Additional Names:
- FLJ12752;OTTHUMP00000207119;RINZF;RINZFC;ZBT10;ZBTB10;Zinc finger and BTB domain containing protein 10;Zinc finger and BTB domain-containing protein 10;Zinc finger protein RIN ZF
- Application:
- Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- RINZF, also known as ZBTB10 (zinc finger and BTB domain containing protein 10), is a 847 amino acid protein that contains one BTB/POZ domain and two C2H2-type zinc fingers. Localized to the nucleus, RINZF is believed to play a role in transcriptional regulation. Specifically, RINZF is capable of binding to the CACC element of the Gastrin promoter. In this regard, RINZF competes with Sp1 for CACC binding and interferes with Sp1 transactivation, thereby regulating Gastrin gene expression. The rat RINZF protein shares 98% homology with the human RINZF protein, suggesting that RINZF is a conserved protein. Due to alternative splicing events, two RINZF isoforms exist. In addition, RINZF may be phosphorylated by ATR or ATM upon DNA damage.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human ZBTB10
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-zbtb10_polyclonal_antibody-e_ab_53220
