VGLL1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-53198-20UL
60 ul
£183.00
E-AB-53198-60UL
120 ul
£272.00
E-AB-53198-120UL
200 ul
£420.00
E-AB-53198-200UL
About this Product
- SKU:
- E-AB-53198
- Additional Names:
- Protein TONDU,TDU,TONDU,Transcription cofactor vestigial like protein 1,Transcription cofactor vestigial-like protein 1,VGL1,VGLL1,Vestigial like 1,Vgl-1,Vgll1,vestigial like 1 homolog (Drosophila)
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 2 mg/ml
- Extra Details:
- The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member, TEF1, and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid, and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes, suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter, and Vgll1 could partially reverse the inhibitory effect of TEF1 in this assay.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human VGLL1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-vgll1_polyclonal_antibody-e_ab_53198
