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Antibodies

SORD Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-53170-20UL
60 ul
£183.00
E-AB-53170-60UL
120 ul
£272.00
E-AB-53170-120UL
200 ul
£420.00
E-AB-53170-200UL
About this Product
SKU:
E-AB-53170
Additional Names:
DHSO,L iditol 2 dehydrogenase,L-iditol 2-dehydrogenase,OTTHUMP00000161939,SDH,SORD,SORD 1,SORD1,Sorbitol dehydrogenase,Sorbitol dehydrogenase 1
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.78 mg/ml
Extra Details:
Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Host:
Rabbit
Immunogen:
Fusion protein of human SORD
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody