HORMAD2 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-53135-20UL
60 ul
£183.00
E-AB-53135-60UL
120 ul
£272.00
E-AB-53135-120UL
200 ul
£420.00
E-AB-53135-200UL
About this Product
- SKU:
- E-AB-53135
- Additional Names:
- 4930529M09Rik,CT46.2,HORM2,HORMA domain containing 2,HORMA domain-containing protein 2,Hormad2,MGC26710,RP23-329P17.4
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.96 mg/ml
- Extra Details:
- Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity).
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human HORMAD2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-hormad2_polyclonal_antibody-e_ab_53135
