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Antibodies

CNOT7 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-53112-20UL
60 ul
£183.00
E-AB-53112-60UL
120 ul
£272.00
E-AB-53112-120UL
200 ul
£420.00
E-AB-53112-200UL
About this Product
SKU:
E-AB-53112
Additional Names:
BTG1 binding factor 1,BTG1-binding factor 1,CAF 1,CAF-1,CAF1,CCR4 NOT transcription complex subunit 7,CCR4 associated factor 1,CCR4-NOT transcription complex subunit ,CCR4-associated factor 1,Carbon catabolite repressor protein (CCR4) associative factor 1
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.96 mg/ml
Extra Details:
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.CNOT7 (CCR4-NOT Transcription Complex Subunit 7) is a Protein Coding gene. Among its related pathways are Deadenylation-dependent mRNA decay and Gene Expression. GO annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is CNOT8.
Host:
Rabbit
Immunogen:
Fusion protein of human CNOT7
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody