HLA-DQB2 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-53101-20UL
60 ul
£183.00
E-AB-53101-60UL
120 ul
£272.00
E-AB-53101-120UL
200 ul
£420.00
E-AB-53101-200UL
About this Product
- SKU:
- E-AB-53101
- Additional Names:
- D, DQ beta 2 (HLA-DXB)), DQ beta 2 chain, DX beta chain, class II,DV19.1 (major histocompatibility complex,DX-beta,HLA DQB1,HLA DXB,HLA class II histocompatibility antigen,major histocompatibility complex
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.26 mg/ml
- Extra Details:
- HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human HLA-DQB2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-hla_dqb2_polyclonal_antibody-e_ab_53101
