GSKIP Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52808-20UL
60 ul
£183.00
E-AB-52808-60UL
120 ul
£272.00
E-AB-52808-120UL
200 ul
£420.00
E-AB-52808-200UL
About this Product
- SKU:
- E-AB-52808
- Additional Names:
- C14ORF129,Chromosome 14 open reading frame 129 ,GSK3-beta interaction protein,GSK3beta interaction protein,GSKIP,MGC4945,UPF0279
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.78 mg/ml
- Extra Details:
- This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human GSKIP
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-gskip_polyclonal_antibody-e_ab_52808
