RBM15 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52783-20UL
60 ul
£183.00
E-AB-52783-60UL
120 ul
£272.00
E-AB-52783-120UL
200 ul
£420.00
E-AB-52783-200UL
About this Product
- SKU:
- E-AB-52783
- Additional Names:
- OTT,OTT1,One twenty two protein,One-twenty two protein 1,Putative RNA-binding protein 15,RBM15,RNA binding motif protein 15,RNA-binding motif protein 15
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.9 mg/ml
- Extra Details:
- RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family,which have repressor function in several signaling pathway,and may bind to RNA through interaction with spliceosome components. It was first described as a 5' translocation partner of the MAL gene in t(1,22)(p13,q13) infant acute megakaryocytic leukemia,and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation,which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation,block the cell cycle,and induce apoptosis in CML cells.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human RBM15
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-rbm15_polyclonal_antibody-e_ab_52783
